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model predictive control toolkit  (MathWorks Inc)


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    Structured Review

    MathWorks Inc model predictive control toolkit
    Open-top light-sheet microscope with electrically tunable lens (ETL) remote focusing under model <t>predictive</t> control. (a) Scan methods for volumetric light-sheet imaging. (i) In the simplest case, a sample is scanned through a static sheet. (ii) An actuated objective lens can follow a scanning light-sheet, which is faster than (i) but inertia limited and can cause problems with water immersion. (iii) Remote focusing optically shifts the focal plane using an active element like an ETL (b). This setup has less inertia and no moving parts at the sample. (c) Long-working distance open-top imaging is achieved using an asymmetric pair of objective lenses coupled with a water immersion fitting. This enables unobstructed imaging across a water-matched barrier such as FEP (above). (d) Maximum intensity projections along the Z (top) and Y (bottom) axes of a worm expressing a pan-neuronal nuclear-localized fluorescent protein positioned in a microfluidic channel as shown in (c). Scale bar 20 µ m. (e) Fast actuation of an ETL induces high frequency oscillation which slows response time. Performance is improved by using model predictive control to optimize drive signals. The controller iteratively optimizes the input signal to the ETL by minimizing simulated output error while obeying system constraints.
    Model Predictive Control Toolkit, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 95/100, based on 353 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/model predictive control toolkit/product/MathWorks Inc
    Average 95 stars, based on 353 article reviews
    model predictive control toolkit - by Bioz Stars, 2026-04
    95/100 stars

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    1) Product Images from "High speed functional imaging with a microfluidics-compatible open-top light-sheet microscope enabled by model predictive control of a tunable lens"

    Article Title: High speed functional imaging with a microfluidics-compatible open-top light-sheet microscope enabled by model predictive control of a tunable lens

    Journal: bioRxiv

    doi: 10.1101/2025.07.23.666439

    Open-top light-sheet microscope with electrically tunable lens (ETL) remote focusing under model predictive control. (a) Scan methods for volumetric light-sheet imaging. (i) In the simplest case, a sample is scanned through a static sheet. (ii) An actuated objective lens can follow a scanning light-sheet, which is faster than (i) but inertia limited and can cause problems with water immersion. (iii) Remote focusing optically shifts the focal plane using an active element like an ETL (b). This setup has less inertia and no moving parts at the sample. (c) Long-working distance open-top imaging is achieved using an asymmetric pair of objective lenses coupled with a water immersion fitting. This enables unobstructed imaging across a water-matched barrier such as FEP (above). (d) Maximum intensity projections along the Z (top) and Y (bottom) axes of a worm expressing a pan-neuronal nuclear-localized fluorescent protein positioned in a microfluidic channel as shown in (c). Scale bar 20 µ m. (e) Fast actuation of an ETL induces high frequency oscillation which slows response time. Performance is improved by using model predictive control to optimize drive signals. The controller iteratively optimizes the input signal to the ETL by minimizing simulated output error while obeying system constraints.
    Figure Legend Snippet: Open-top light-sheet microscope with electrically tunable lens (ETL) remote focusing under model predictive control. (a) Scan methods for volumetric light-sheet imaging. (i) In the simplest case, a sample is scanned through a static sheet. (ii) An actuated objective lens can follow a scanning light-sheet, which is faster than (i) but inertia limited and can cause problems with water immersion. (iii) Remote focusing optically shifts the focal plane using an active element like an ETL (b). This setup has less inertia and no moving parts at the sample. (c) Long-working distance open-top imaging is achieved using an asymmetric pair of objective lenses coupled with a water immersion fitting. This enables unobstructed imaging across a water-matched barrier such as FEP (above). (d) Maximum intensity projections along the Z (top) and Y (bottom) axes of a worm expressing a pan-neuronal nuclear-localized fluorescent protein positioned in a microfluidic channel as shown in (c). Scale bar 20 µ m. (e) Fast actuation of an ETL induces high frequency oscillation which slows response time. Performance is improved by using model predictive control to optimize drive signals. The controller iteratively optimizes the input signal to the ETL by minimizing simulated output error while obeying system constraints.

    Techniques Used: Microscopy, Control, Imaging, Expressing



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    model predictive control toolkit  (MathWorks Inc)
    95
    MathWorks Inc model predictive control toolkit
    Open-top light-sheet microscope with electrically tunable lens (ETL) remote focusing under model <t>predictive</t> control. (a) Scan methods for volumetric light-sheet imaging. (i) In the simplest case, a sample is scanned through a static sheet. (ii) An actuated objective lens can follow a scanning light-sheet, which is faster than (i) but inertia limited and can cause problems with water immersion. (iii) Remote focusing optically shifts the focal plane using an active element like an ETL (b). This setup has less inertia and no moving parts at the sample. (c) Long-working distance open-top imaging is achieved using an asymmetric pair of objective lenses coupled with a water immersion fitting. This enables unobstructed imaging across a water-matched barrier such as FEP (above). (d) Maximum intensity projections along the Z (top) and Y (bottom) axes of a worm expressing a pan-neuronal nuclear-localized fluorescent protein positioned in a microfluidic channel as shown in (c). Scale bar 20 µ m. (e) Fast actuation of an ETL induces high frequency oscillation which slows response time. Performance is improved by using model predictive control to optimize drive signals. The controller iteratively optimizes the input signal to the ETL by minimizing simulated output error while obeying system constraints.
    Model Predictive Control Toolkit, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/model predictive control toolkit/product/MathWorks Inc
    Average 95 stars, based on 1 article reviews
    model predictive control toolkit - by Bioz Stars, 2026-04
    95/100 stars
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    Open-top light-sheet microscope with electrically tunable lens (ETL) remote focusing under model predictive control. (a) Scan methods for volumetric light-sheet imaging. (i) In the simplest case, a sample is scanned through a static sheet. (ii) An actuated objective lens can follow a scanning light-sheet, which is faster than (i) but inertia limited and can cause problems with water immersion. (iii) Remote focusing optically shifts the focal plane using an active element like an ETL (b). This setup has less inertia and no moving parts at the sample. (c) Long-working distance open-top imaging is achieved using an asymmetric pair of objective lenses coupled with a water immersion fitting. This enables unobstructed imaging across a water-matched barrier such as FEP (above). (d) Maximum intensity projections along the Z (top) and Y (bottom) axes of a worm expressing a pan-neuronal nuclear-localized fluorescent protein positioned in a microfluidic channel as shown in (c). Scale bar 20 µ m. (e) Fast actuation of an ETL induces high frequency oscillation which slows response time. Performance is improved by using model predictive control to optimize drive signals. The controller iteratively optimizes the input signal to the ETL by minimizing simulated output error while obeying system constraints.

    Journal: bioRxiv

    Article Title: High speed functional imaging with a microfluidics-compatible open-top light-sheet microscope enabled by model predictive control of a tunable lens

    doi: 10.1101/2025.07.23.666439

    Figure Lengend Snippet: Open-top light-sheet microscope with electrically tunable lens (ETL) remote focusing under model predictive control. (a) Scan methods for volumetric light-sheet imaging. (i) In the simplest case, a sample is scanned through a static sheet. (ii) An actuated objective lens can follow a scanning light-sheet, which is faster than (i) but inertia limited and can cause problems with water immersion. (iii) Remote focusing optically shifts the focal plane using an active element like an ETL (b). This setup has less inertia and no moving parts at the sample. (c) Long-working distance open-top imaging is achieved using an asymmetric pair of objective lenses coupled with a water immersion fitting. This enables unobstructed imaging across a water-matched barrier such as FEP (above). (d) Maximum intensity projections along the Z (top) and Y (bottom) axes of a worm expressing a pan-neuronal nuclear-localized fluorescent protein positioned in a microfluidic channel as shown in (c). Scale bar 20 µ m. (e) Fast actuation of an ETL induces high frequency oscillation which slows response time. Performance is improved by using model predictive control to optimize drive signals. The controller iteratively optimizes the input signal to the ETL by minimizing simulated output error while obeying system constraints.

    Article Snippet: Finally, we used the generated model to construct a model predictive controller using the MATLAB Model Predictive Control toolkit.

    Techniques: Microscopy, Control, Imaging, Expressing